DEDiscover: A Computation and Simulation Tool for HIV Viral Fitness Research

Viral fitness is one of the most important areas in HIV virology research. Modeling viral fitness poses significant computational challenges which must be solved in order to appropriately design and analyze experimental data. To facilitate the HIV viral fitness research, we have designed a computation and simulation tool, DEDiscover, to deal with both simulation and estimation problems for ordinary and delay differential equation models. In this paper, we describe the design and features of DEDiscover and demonstrate how it may be used to analyze the results of an HIV viral fitness experiment.