Title :
NutriGeneOntology: A Biomedical Ontology for Nutrigenomics Research
Author :
Fabregat, Antonio ; Arregui, Maria ; Barrera, Elisabet ; Portoles, O. ; Corella, Dolores ; Coltell, Oscar
Author_Institution :
Dept. of Comput. Languages & Syst., Univ. Jaume I, Castellon
Abstract :
Currently, in Nutritional Genomics it is crucial to have computing models and solutions and technological platforms in order to support acquisition, storage, management and presentation of all the information generated. Our aim is to build a biomedical ontology in order to formalise and integrate genomic, environmental and phenotypic data applied to Nutritional Genomics research focused on cardiovascular diseases and related phenotypes. Four different food composition tables have been employed to estimate the amount of nutrients provided by the diet. Web engineering technologies have been applied for constructing the Web platform containing the ontology, which integrates three distinct ontologies offering the corresponding models and services: food composition table alignment, gene-environment interaction, and cardiovascular risk estimation.
Keywords :
Internet; biochemistry; cardiovascular system; diseases; genetics; medical information systems; ontologies (artificial intelligence); Health Information System; NutriGeneOntology; Web engineering technologies; Web platform; biomedical ontology; cardiovascular diseases; cardiovascular risk estimation; environmental data; food composition tables; gene-environment interaction; nutritional genomics research; phenotypic data; Bioinformatics; Biomedical computing; Biomedical engineering; Cardiovascular diseases; Computer languages; Databases; Environmental factors; Genomics; Java; Ontologies; Biomedical Ontology; Framingham risk equation; Gene-diet interaction; Medical; NutriGenOntology; Nutritional Epidemiology; genomic and environmental data integration;
Conference_Titel :
BioMedical Engineering and Informatics, 2008. BMEI 2008. International Conference on
Conference_Location :
Sanya
Print_ISBN :
978-0-7695-3118-2
DOI :
10.1109/BMEI.2008.315