In Vivo Proton Magnetic Resonance Spectroscopic Study of the Healthy Chinese Adult Pons

This paper aims to detect the normal standard of metabolic ratios in the Pons of healthy adult Chinese subjects by using proton magnetic resonance spectroscopy (1HMRS). Eighty healthy Chinese subjects were divided into four groups, containing of 20 subjects per decade, ranging 21 to 60 years. Spectra were obtained from at 1.5 T MR scanner by using a PRESS sequence with Repetition Time (TR)/ Echo Time (TE) of 1500/144 ms. Results: The total mean ratios of N-acetylasparate/ creatine- phosphocreatine(NAA/Cr), NAA/Cr+ choline- containing compound(Cho) and Cho/Cr in subjects ranging from 21 to 60 years were 2.127plusmn0.071, 0.811plusmn0.059 and 1.814plusmn0094, respectively. The metabolic ratios in men were higher than in women. However, there was no significant difference with respect to age or gender. The ratios of NAA/Cr, NAA/Cr+Cho, Cho/Cr in the Pons did not correlate with age or gender of healthy subjects.