Title :
Removing water artefacts from 2D protein NMR spectra using GEVD with congruent matrix pencils
Author :
Stadlthanner, K. ; Tomé, A.M. ; Theis, F.J. ; Gronwald, K. ; Kalbitzer, H.-R. ; Lang, E.W.
Author_Institution :
Inst. of Biophys., Regensburg Univ., Germany
Abstract :
Multidimensional H nmr spectra of biomolecules dissolved in light water are contaminated by an intense water artefact. We discuss the application of the generalized eigenvalue decomposition (GEVD) method using a matrix pencil to explore the time structure of the signals in order to separate out the water artefacts. Simulated as well as experimental 2D NOESY spectra of proteins are studied. Results are compared to those obtained with the FastICA algorithm.
Keywords :
NMR spectroscopy; biological NMR; eigenvalues and eigenfunctions; macromolecules; matrix algebra; proteins; signal processing; water; 2D protein NMR spectra; GEVD; biomolecules; generalized eigenvalue decomposition method; matrix pencils; nuclear magnetic resonance; water artefact removal; water resonance; Chemicals; Dynamic range; Embedded computing; Multidimensional systems; Nuclear magnetic resonance; Proteins; Protons; Signal processing; Water pollution; Water resources;
Conference_Titel :
Signal Processing and Its Applications, 2003. Proceedings. Seventh International Symposium on
Print_ISBN :
0-7803-7946-2
DOI :
10.1109/ISSPA.2003.1224821
