Simulation of tissue resistivity behavior using a finite difference based model

Author

Rao, Suneel P. ; Kun, Stevan ; Peura, Robert A.

Author_Institution

Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA

fYear

1994

fDate

17-18 Mar 1994

Firstpage

116

Lastpage

117

Abstract

Biological tissues are morphologically and physiologically very complex. From an electrical point of view, they are anisotropic and can also be inhomogeneous. Due to their highly complex properties, it is extremely difficult to model their resistivity behavior using analytical models. This can be overcome by adopting numerical techniques to solve the problem. A numerical model based on the finite difference method has been developed. It models the resistivity behavior of both skeletal and cardiac muscle of different levels of anisotropy and/or inhomogeneity. Simulations of skeletal muscle behavior mere performed and compared with the results of a validated analytical model. Results obtained with two models agree within ±10% The model is being evaluated using ex vivo experimental measurements

Keywords

bioelectric phenomena; cardiology; finite difference methods; muscle; physiological models; anisotropic material; biological tissues; cardiac muscle; ex vivo experimental measurements; finite difference based model; inhomogeneity; numerical techniques; skeletal muscle; tissue resistivity behavior simulation; Analytical models; Anisotropic magnetoresistance; Biological system modeling; Biological tissues; Boundary conditions; Conductivity; Equations; Finite difference methods; Numerical models; Sparse matrices;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1994., Proceedings of the 1994 20th Annual Northeast

Conference_Location

Springfield, MA

Print_ISBN

0-7803-1930-3

Type

conf

DOI

10.1109/NEBC.1994.305153

Filename

305153