Modulation of paired-pulse responses in the dentate gyrus: vigilance state effects

Author

Blaise, J. Harry ; Bronzino, Joseph D. ; Morgane, Peter J.

Author_Institution

Biomed. Eng. Graduate Program, Connecticut Univ., Storrs, CT, USA

fYear

1998

fDate

9-10 Apr 1998

Firstpage

1

Lastpage

2

Abstract

This study was undertaken to assess the effects of vigilance state on measures of the paired-pulse response recorded in the dentate granule cell layer of the hippocampal formation in freely moving rats. Paired-pulse stimulation of the medial perforant pathway was used to construct a paired-pulse index (PPI) for 15-, 30- and 90-day old animals during the vigilance states of quiet waking, slow-wave sleep, and rapid eye movement sleep. Results indicate that at each age there is no significant difference in PPI values across the range of interpulse intervals selected

Keywords

bioelectric potentials; brain; cellular biophysics; neurophysiology; sleep; 0.041 to 0.246 y; dentate gyrus; freely moving rats; hippocampal formation; interpulse intervals; paired-pulse index; paired-pulse responses modulation; quiet waking; rapid eye movement sleep; slow-wave sleep; vigilance state effects; Biomedical engineering; Biomedical measurements; Educational institutions; Electrodes; Feedforward systems; Pulse amplifiers; Rats; Signal analysis; Sleep; Space vector pulse width modulation;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1998. Proceedings of the IEEE 24th Annual Northeast

Conference_Location

Hershey, PA

Print_ISBN

0-7803-4544-4

Type

conf

DOI

10.1109/NEBC.1998.664856

Filename

664856