Title :
3-D Deep penetration photoacoustic imaging with a 2-D CMUT array
Author :
Ma, Te-Jen ; Kothapalli, Rajasekhar ; Vaithilingam, Srikant ; Oralkan, Ömer ; Kamaya, Aya ; Wygant, Ira O. ; Zhuang, Xuefeng ; Gambhir, Sanjiv S. ; Jeffrey, R. Brooke, Jr. ; Khuri-Yakub, Butrus T.
Author_Institution :
Edward L. Ginzton Lab., Stanford Univ., Stanford, CA, USA
Abstract :
In this work, we demonstrate 3-D photoacoustic imaging of optically absorbing targets embedded as deep as 5 cm inside a highly scattering background medium using a 2-D capacitive micromachined ultrasonic transducer (CMUT) array with a center frequency of 5.5 MHz. 3-D volumetric images and 2-D maximum intensity projection images are presented to show the objects imaged at different depths. Due to the close proximity of the CMUT to the integrated frontend circuits, the CMUT array imaging system has a low noise floor. This makes the CMUT a promising technology for deep tissue photoacoustic imaging.
Keywords :
bio-optics; bioacoustics; capacitive sensors; photoacoustic effect; ultrasonic transducer arrays; 2D CMUT array; 2D capacitive micromachined ultrasonic transducer array; 2D maximum intensity projection image; 3D deep penetration photoacoustic imaging; 3D volumetric image; frequency 5.5 MHz; highly scattering background medium; optically absorbing target; Acoustics; Arrays; Biomedical optical imaging; Hair; Phantoms; Pump lasers;
Conference_Titel :
Ultrasonics Symposium (IUS), 2010 IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4577-0382-9
DOI :
10.1109/ULTSYM.2010.5935647