Title :
Return-to-the-origin probability imaging as indicator of local necrosis
Author :
Meiler, M. ; Helmer, K.G. ; Sotak, C.H.
Author_Institution :
Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA
Abstract :
The object of this work is to develop a noninvasive method for detecting local tissue necrosis in RIF-1 murine tumors. The method is based on structural differences between necrotic and viable tissue. By probing the displacement of water molecules in a time, t, it is possible to gather information on the tissue structure. This can be exploited to detect local tissue necrosis in tumors. The return-to-the-origin probability derived from porous media theory is employed to detect local necrosis in tumor
Keywords :
biological NMR; biological techniques; probability; tumours; RIF-1 murine tumors; local necrosis indicator; porous media theory; return-to-the-origin probability imaging; tissue structure information; viable tissue; water molecules displacement; Biochemistry; Biomedical applications of radiation; Biomedical engineering; Drugs; Gyromagnetism; Medical treatment; Neoplasms; Nuclear magnetic resonance; Patient monitoring; Radiation monitoring;
Conference_Titel :
Bioengineering Conference, 1998. Proceedings of the IEEE 24th Annual Northeast
Conference_Location :
Hershey, PA
Print_ISBN :
0-7803-4544-4
DOI :
10.1109/NEBC.1998.664880
