Tissue ischemia measurement using induced current impedance spectroscopy: non-contact system design

Impedance spectroscopy is a promising method for tissue ischemia measurement. Ischemia alters physiological and biochemical tissue properties, which change tissue impedance. This can be detected and monitored using impedance spectroscopic measurement methods. The authors have developed a system for non-invasive ischemia measurements, based on injected current impedance spectroscopy. The overall goal of the present research is to develop a noninvasive, non-contact, fully-automated portable device for muscle tissue ischemia measurement, monitoring and imaging, based on induced current impedance spectroscopy. In the course of this research, the authors will develop models and implement a device that will use eddy current impedance spectroscopic techniques to measure the impedance of small volume samples of tissue. Here, the authors present the basic impedance spectroscopic principles, eddy current imaging fundamentals. The authors propose a basic system design, and discuss the major differences between induced and injected current impedance spectroscopy