Title :
Design of a Holding System for Micro-coil based MRI
Author :
Ekekwe, N. ; Armiger, B. ; Murray, K.
Author_Institution :
Johns Hopkins Univ., Baltimore
fDate :
Aug. 12 2007-July 16 2007
Abstract :
We report the design and fabrication of a holding cell system that enables concurrent image visualization of a single cell during planar micro-coil based magnetic resonance imaging (MRI) at cellular level. The present hardware design of many micro-coil based MRI systems prevents monitoring of cell interactions and compositions during MRI. The system, fabricated on a poly dimethyl siloxane (PDMS) structure using soft lithography on a glass substrate, is designed to solve this problem. To test it, a laser beam would be coupled into the chip to acquire images of a frog oocyte.
Keywords :
biological techniques; cellular biophysics; sample holders; soft lithography; cell interactions; concurrent image visualization; frog oocyte; glass substrate; holding system design; laser beam coupling; magnetic resonance imaging; microcoil based MRI; poly dimethyl siloxane; single cell visualization; soft lithography; Fabrication; Glass; Hardware; Laser beams; Magnetic resonance imaging; Monitoring; Optical coupling; Soft lithography; Testing; Visualization; MRI; planar coil; soft lithography;
Conference_Titel :
Optical MEMS and Nanophotonics, 2007 IEEE/LEOS International Conference on
Conference_Location :
Hualien
Print_ISBN :
978-1-4244-0641-8
DOI :
10.1109/OMEMS.2007.4373846
