Title :
An interdigitated electrode detector for the identification of a single specific DNA molecule fragment
Author :
Fuller, Lynn F. ; Vega, Reinaldo ; Manley, Robert ; Hwang, Vee Chee ; Jaeger, Dan ; Pham, An ; Wescott, Nate ; Connolly, Mike
Author_Institution :
Microelectron. Eng., Rochester Inst. of Technol., NY, USA
fDate :
30 June-2 July 2003
Abstract :
The detection of a single specific DNA molecule fragment will allow for the identification of bacteria and viruses that could be harmful if not detected quickly. DNA probes attached to the sensor electrodes have a specific molecular sequence that results in a billion to one or better probability that any DNA that hybridizes with the probe is the DNA to be detected. The DNA is coated with a metal, resulting in a large decrease in the measured electrical resistance between the sensor electrodes. Thus the electrical detection of a specific single DNA molecule fragment is very easy.
Keywords :
DNA; biomedical electrodes; biosensors; electrical resistivity; gold; sensors; Au; DNA molecule fragment; DNA probes; bacteria; electrical detection; electrical resistance; interdigitated electrode detector; viruses; DNA; Detectors; Electric resistance; Electric variables measurement; Electrical resistance measurement; Electrodes; Microorganisms; Probes; Sequences; Viruses (medical);
Conference_Titel :
University/Government/Industry Microelectronics Symposium, 2003. Proceedings of the 15th Biennial
Print_ISBN :
0-7803-7972-1
DOI :
10.1109/UGIM.2003.1225725