An evaluation of single dipole solutions to extended sources in EEG and MEG

Author

Huiskamp, Geertjan

Author_Institution

Dept. of Neurology & Neurosurg., Univ. Med. Center Utrecht, Netherlands

fYear

2011

fDate

13-16 May 2011

Firstpage

32

Lastpage

34

Abstract

Interictal spikes as observed in epilepsy patients are assumed to be generated by relatively large patches of activated cortex. In order to check the validity of single dipole solutions to such spikes in EEG and MEG a simulation study is performed in a realistically shaped cortical model. It is shown that both in EEG and MEG the center of activated cortex can be misrepresented by single dipole solutions by more then 1 cm. The geometry of sulci and gyri determines where, for which modality, this effect is larger.

Keywords

brain models; diseases; electroencephalography; magnetoencephalography; neurophysiology; EEG; MEG; epilepsy patients; gyri geometry; interictal spikes; realistically shaped cortical model; single dipole solutions; sulci ageometry; Brain models; Computational modeling; Electrodes; Electroencephalography; Epilepsy; Geometry; EEG; MEG; dipole; epilepsy; interictal spikes; source modeling;

fLanguage

English

Publisher

ieee

Conference_Titel

Noninvasive Functional Source Imaging of the Brain and Heart & 2011 8th International Conference on Bioelectromagnetism (NFSI & ICBEM), 2011 8th International Symposium on

Conference_Location

Banff, AB

Print_ISBN

978-1-4244-8282-5

Type

conf

DOI

10.1109/NFSI.2011.5936814

Filename

5936814