Title :
Run-to-run control strategy for diabetes management
Author :
Doyle, F.J. ; Srinivasan, B. ; Bonvin, D.
Author_Institution :
Dept. of Chem. Eng., Delaware Univ., Newark, DE, USA
Abstract :
An approach to insulin injection therapy is introduced that draws from recent ideas in run-to-run control of batch chemical reactors. The method relies on measurements of blood glucose and does not require a mathematical model. Results are shown for simulation case studies involving a detailed pharmacokinetic model.
Keywords :
biomedical measurement; blood; diseases; medical control systems; organic compounds; patient treatment; Type I diabetes mellitus; batch chemical reactors; blood glucose measurements; detailed pharmacokinetic model; diabetes management; mathematical model; run-to-run control strategy; simulation case studies; Biomedical measurements; Blood; Diabetes; Diseases; Fluctuations; Insulin; Medical treatment; Protocols; Sugar; Timing;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1019492