DocumentCode
1990125
Title
Methodology for Evaluating DNA Pattern Searching Algorithms on Multiprocessor
Author
Soewito, Benfano ; Weng, Ning
Author_Institution
Southern Illinois Univ., Carbondale
fYear
2007
fDate
14-17 Oct. 2007
Firstpage
570
Lastpage
577
Abstract
Pattern matching has been one of the major operations in modern bioengineering especially in Bioinformatics. Prior work on this area have focus on either pursuing mathematically efficient matching algorithms or hardwired approach. As multicore processor are becoming mainstream, developers need to determine how to take advantage of multicore technology for pattern matching. In this paper, we propose a methodology to evaluate pattern search algorithms for DNA on Multiprocessor. Our evaluation methodology is an automatic simulation framework. Starting from a uniprocessor profiling, the framework constructs task graphs for string matching algorithms. Then task graphs are mapped onto multiprocessor. The system´s performance is determined by the analytical performance model. With this framework, we can evaluate the performance of different algorithms on multiprocessor. Our case studies show that finite automaton based (Aho-Corasick) is more efficient than shift table based algorithms (SFKSearch and Wu-Manber) on uniprocessor, however, Wu-Manber is 3 times efficient than Aho-Corasick on multiprocessor due to its inherent parallelism.
Keywords
DNA; biology computing; cellular biophysics; molecular biophysics; pattern matching; DNA pattern searching algorithms; bioengineering; bioinformatics; finite automaton based algorithms; multiprocessor; pattern matching; shift table based algorithms; string matching algorithms; task graphs; uniprocessor profiling; Application specific integrated circuits; Bioinformatics; Computer networks; DNA computing; Databases; Genomics; Multicore processing; Parallel processing; Pattern matching; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location
Boston, MA
Print_ISBN
978-1-4244-1509-0
Type
conf
DOI
10.1109/BIBE.2007.4375618
Filename
4375618
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