• DocumentCode
    1991248
  • Title

    αCORR: a novel algorithm for clustering gene expression data

  • Author

    Sharara, Hossam S. ; Ismail, Mohamed A.

  • Author_Institution
    Alexandria Univ., Alexandria
  • fYear
    2007
  • fDate
    14-17 Oct. 2007
  • Firstpage
    974
  • Lastpage
    981
  • Abstract
    Recent advances in biotechnology allow researchers to measure expression levels for thousands of genes simultaneously, across different conditions and over time. Analysis of data produced by such experiments offers potential insight into gene function and regulatory mechanisms. A key step in the analysis of gene expression data is the detection of groups of genes that manifest similar expression patterns. The corresponding algorithmic problem is to cluster multi-condition gene expression patterns. This paper aims to introduce a new clustering algorithm for gene expression data. The design of the proposed algorithm tries to avoid some of the drawbacks and the disadvantages of the present algorithms of clustering gene expression data. The proposed αCORRclustering algorithm is tested and verified on real biological data sets.
  • Keywords
    biology computing; cellular biophysics; genetics; molecular biophysics; αCORR; clustering algorithm; data clustering; gene expression; gene function; gene regulatory; Algorithm design and analysis; Bioinformatics; Clustering algorithms; Data analysis; Data engineering; Gene expression; Genomics; Shape measurement; Systems engineering and theory; Time sharing computer systems;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
  • Conference_Location
    Boston, MA
  • Print_ISBN
    978-1-4244-1509-0
  • Type

    conf

  • DOI
    10.1109/BIBE.2007.4375676
  • Filename
    4375676