DocumentCode :
1991248
Title :
αCORR: a novel algorithm for clustering gene expression data
Author :
Sharara, Hossam S. ; Ismail, Mohamed A.
Author_Institution :
Alexandria Univ., Alexandria
fYear :
2007
fDate :
14-17 Oct. 2007
Firstpage :
974
Lastpage :
981
Abstract :
Recent advances in biotechnology allow researchers to measure expression levels for thousands of genes simultaneously, across different conditions and over time. Analysis of data produced by such experiments offers potential insight into gene function and regulatory mechanisms. A key step in the analysis of gene expression data is the detection of groups of genes that manifest similar expression patterns. The corresponding algorithmic problem is to cluster multi-condition gene expression patterns. This paper aims to introduce a new clustering algorithm for gene expression data. The design of the proposed algorithm tries to avoid some of the drawbacks and the disadvantages of the present algorithms of clustering gene expression data. The proposed αCORRclustering algorithm is tested and verified on real biological data sets.
Keywords :
biology computing; cellular biophysics; genetics; molecular biophysics; αCORR; clustering algorithm; data clustering; gene expression; gene function; gene regulatory; Algorithm design and analysis; Bioinformatics; Clustering algorithms; Data analysis; Data engineering; Gene expression; Genomics; Shape measurement; Systems engineering and theory; Time sharing computer systems;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-1509-0
Type :
conf
DOI :
10.1109/BIBE.2007.4375676
Filename :
4375676
Link To Document :
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