Title :
MS Lesions Detection in MRI Using Grouping Artificial Immune Networks
Author :
Younis, Akmal A. ; Soliman, Ahmed T. ; Kabuka, Mansur R. ; John, Nigel M.
Author_Institution :
Univ. of Miami, Miami
Abstract :
A dual-channel 3D MRI segmentation technique based on grouping artificial immune networks (GAIN) is introduced to detect MS lesion in MR images. The technique demonstrates the ability of artificial immune networks to handle MS lesions detection in T1- and T2-weighted brain MRI. The GAIN-based MRI segmentation technique was evaluated using simulated MS brain images from the McConnell Brain Imaging Centre, Montreal Neurological Institute of McGill University. 3D anisotropic filtering is used to handle noise artifacts in the simulated 3D MRI data sets. Experimental results demonstrated that dual channel MS segmentation approach exhibited high accuracy in segmenting the simulated MS brain data and an even higher accuracy when compared to techniques based on single channel 3D MRI data sets in terms of the Dice coefficient, an objective measure of overlap.
Keywords :
artificial immune systems; biomedical MRI; brain; diseases; medical computing; 3D anisotropic filtering; Dice coefficient; dual-channel 3D MRI segmentation technique; grouping artificial immune networks; magnetic resonance images; multiple sclerosis lesions detection; simulated MS brain images; Brain modeling; Clinical trials; Image analysis; Image segmentation; Lesions; Magnetic analysis; Magnetic resonance imaging; Multiple sclerosis; Rendering (computer graphics); Robustness;
Conference_Titel :
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-1509-0
DOI :
10.1109/BIBE.2007.4375704