• DocumentCode
    1991984
  • Title

    A Suffix Tree Construction Algorithm for DNA Sequences

  • Author

    Huo, Hongwei ; Stojkovic, Vojislav

  • Author_Institution
    School of Computer Science and Technology, Xidian University, Xi´an 710071, China. hwhuo@mail.xidian.edu.cn
  • fYear
    2007
  • fDate
    14-17 Oct. 2007
  • Firstpage
    1178
  • Lastpage
    1182
  • Abstract
    The suffix tree is a powerful data structure in string processing and DNA sequence comparisons. However, constructing suffix trees being very greedy in space is a fatal drawback. In addition, the performance of the suffix tree construction using suffix link will rapidly degrade with the increase of the scale of sequences to be handled because of the random access. In order to overcome these disadvantages, a new bit layout is used for the nodes of a suffix tree which has less space requirements. Based on this an algorithm to construct suffix tree for DNA sequences is proposed using partitioning strategies. The effectiveness for the proposed algorithm is shown in the testing cases from NCBI web site. Comparisons with Kurtz´s algorithm in space requirements and running time have been made in the experiments. The results show that the proposed algorithm is memory-efficient and has a better performance over Kurtz´s algorithm on the average running time.
  • Keywords
    DNA; biology computing; tree data structures; DNA sequences; Kurtz algorithm; NCBI web site; bit layout; string processing; suffix tree construction algorithm; Binary search trees; Bioinformatics; Computer science; DNA; Degradation; Genomics; Partitioning algorithms; Performance loss; Sequences; Tree data structures;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
  • Conference_Location
    Boston, MA
  • Print_ISBN
    978-1-4244-1509-0
  • Type

    conf

  • DOI
    10.1109/BIBE.2007.4375711
  • Filename
    4375711