Title :
A Modified Uniformization Method for the Chemical Master Equation
Author :
Zhang, Jingwei ; Watson, Layne T.
Author_Institution :
Virginia Polytech. Inst. & State Univ., Blacksburg
Abstract :
The chemical master equation is considered an accurate description of general chemical systems, and especially so for modeling cell cycle and gene regulatory networks. This paper proposes an efficient way of solving the chemical master equation for some prototypical problems in systems biology. A comparison between this new approach and some traditional approaches is also given.
Keywords :
biochemistry; cellular biophysics; genetics; master equation; cell cycle; chemical master equation; gene regulatory networks; general chemical systems; systems biology; Biological system modeling; Chemical analysis; Computational modeling; Computer science; Differential equations; Mathematical model; Mathematics; Partial differential equations; Random variables; Stochastic processes;
Conference_Titel :
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Conference_Location :
Boston, MA
Print_ISBN :
978-1-4244-1509-0
DOI :
10.1109/BIBE.2007.4375761
