Title :
Non-rigid motion analysis and feature labelling of the growth cone
Author :
Gwydir, Stacy H. ; Buettner, Helen M. ; Dunn, Stanley M.
Author_Institution :
Rutgers Univ., Newark, NJ, USA
Abstract :
Quantitative analysis of neurite outgrowth provides key information for the development of new therapeutic strategies for treating nerve injury. The motion of the growth cone, the growing tip of a neurite, can be characterized as non-rigid, since its contour is constantly deforming. The goal of this research is to track the motion of the growth cone, using active contours and feature labelling, to provide quantitative analysis of specific neurite modalities, and ultimately to predict the motion of the growth cone
Keywords :
biological techniques and instruments; cellular transport and dynamics; neurophysiology; optical microscopy; active contours; feature labelling; growth cone motion; nerve injury treatment; neurite outgrowth; nonrigid motion analysis; quantitative analysis; therapeutic strategies; videotape-recorded optical microscope images; Active contours; Biomedical optical imaging; Deformable models; Information analysis; Injuries; Labeling; Motion analysis; Nerve fibers; Neurons; Tracking;
Conference_Titel :
Biomedical Image Analysis, 1994., Proceedings of the IEEE Workshop on
Conference_Location :
Seattle, WA
Print_ISBN :
0-8186-5802-9
DOI :
10.1109/BIA.1994.315863
