Positive and negative effects of ventricular ejection

Author

Danielsen, Michael ; Palladino, Joseph L. ; Noordergraaf, Abraham

Author_Institution

Dept. of Eng. & Comput. Sci., Trinity Coll., Hartford, CT, USA

fYear

2000

fDate

2000

Firstpage

33

Lastpage

34

Abstract

By allowing a model based on isovolumic heart properties to eject into an arterial load we identify an ejection effect consisting of deactivation and hyperactivation phenomena. The ejection effect implies that ventricular ejection exerts both positive and negative effects on ventricular pressure generation. The ejection effect is interpreted as alterations in the underlying contractile properties of the ventricle. A new flow dependent mathematical model of the ejection effect is presented

Keywords

cardiovascular system; muscle; physiological models; arterial load; deactivation phenomena; flow dependent mathematical model; hyperactivation phenomena; isovolumic heart properties; negative effects; positive effects; underlying contractile properties; ventricular ejection; ventricular pressure generation; Cardiology; Educational institutions; Heart rate; Humans; Mathematical model; Muscles; Myocardium; Pollution measurement; Predictive models; Pressure measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2000. Proceedings of the IEEE 26th Annual Northeast

Conference_Location

Storrs, CT

Print_ISBN

0-7803-6341-8

Type

conf

DOI

10.1109/NEBC.2000.842365

Filename

842365