Title :
Positive and negative effects of ventricular ejection
Author :
Danielsen, Michael ; Palladino, Joseph L. ; Noordergraaf, Abraham
Author_Institution :
Dept. of Eng. & Comput. Sci., Trinity Coll., Hartford, CT, USA
Abstract :
By allowing a model based on isovolumic heart properties to eject into an arterial load we identify an ejection effect consisting of deactivation and hyperactivation phenomena. The ejection effect implies that ventricular ejection exerts both positive and negative effects on ventricular pressure generation. The ejection effect is interpreted as alterations in the underlying contractile properties of the ventricle. A new flow dependent mathematical model of the ejection effect is presented
Keywords :
cardiovascular system; muscle; physiological models; arterial load; deactivation phenomena; flow dependent mathematical model; hyperactivation phenomena; isovolumic heart properties; negative effects; positive effects; underlying contractile properties; ventricular ejection; ventricular pressure generation; Cardiology; Educational institutions; Heart rate; Humans; Mathematical model; Muscles; Myocardium; Pollution measurement; Predictive models; Pressure measurement;
Conference_Titel :
Bioengineering Conference, 2000. Proceedings of the IEEE 26th Annual Northeast
Conference_Location :
Storrs, CT
Print_ISBN :
0-7803-6341-8
DOI :
10.1109/NEBC.2000.842365
