Title :
High resolution, high speed venographic MR imaging using susceptibility effect
Author :
Lai, Song ; Wang, Jiongjiong ; Jahng, Geon-Ho
Author_Institution :
Dept. of Diagnostic Imaging & Therapeutics, Connecticut Univ., Farmington, CT, USA
Abstract :
A new technique for imaging venous vasculature is described. The technique explores the use of paramagnetic deoxyhemoglobin (Hb) in blood as an endogenous contrast agent. The presence of Hb induces magnetic field inhomogeneity within and surrounding venous blood vessels. This in turn results in water proton spin phase dispersion and consequently signal attenuation in and around venous vessels in a gradient echo image. Using high resolution susceptibility-sensitized echo planar MRI pulse sequences, whole brain venographic images based on this contrast mechanism can be obtained within a few seconds. The new method holds great potential for applications in both basic research and clinical arena
Keywords :
biomedical MRI; blood vessels; brain; image resolution; medical image processing; endogenous contrast agent; gradient echo image; high resolution imaging; high speed venographic MRI; magnetic field inhomogeneity; paramagnetic deoxyhemoglobin; signal attenuation; susceptibility effect; susceptibility-sensitized echo planar sequences; venous vasculature imaging; water proton spin phase dispersion; whole brain venographic images; Attenuation; Biomedical imaging; Blood vessels; High-resolution imaging; Image resolution; Magnetic fields; Magnetic resonance imaging; Paramagnetic materials; Protons; Signal resolution;
Conference_Titel :
Bioengineering Conference, 2000. Proceedings of the IEEE 26th Annual Northeast
Conference_Location :
Storrs, CT
Print_ISBN :
0-7803-6341-8
DOI :
10.1109/NEBC.2000.842392
