• DocumentCode
    1998889
  • Title

    Stability analysis of SSN biochemical networks

  • Author

    Su, Wei ; Lu, Jinhu ; Ogorzalek, Maciej J.

  • Author_Institution
    Inst. of Syst. Sci., Acad. Math. & Syst. Sci., Beijing, China
  • fYear
    2011
  • fDate
    15-18 May 2011
  • Firstpage
    2677
  • Lastpage
    2680
  • Abstract
    This paper further investigates the dynamical properties of a class of basic biochemical networks modules - single substrate and single product with no inhibition (SSN) module. It is well known that the biological networks can be modelled by using different kinetics according to their reaction types. This paper introduces the SSN model under the law of mass action and proves that it can admit uniquely globally asymptotically stable positive equilibrium. Moreover, we prove that the SSN module under Hill kinetics can admit uniquely asymptotically stable positive equilibrium. It indicates some potential applications in the understanding of some biological networks modules and the design of some specific network controllers.
  • Keywords
    biochemistry; molecular biophysics; physiological models; reaction kinetics theory; Hill kinetics; SSN biochemical networks; globally asymptotically stable positive equilibrium; inhibition; kinetics; mass action; reaction types; single product; single substrate; specific network controllers; stability analysis; Asymptotic stability; Biology; Equations; Kinetic theory; Mathematical model; Silicon; Stability analysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Circuits and Systems (ISCAS), 2011 IEEE International Symposium on
  • Conference_Location
    Rio de Janeiro
  • ISSN
    0271-4302
  • Print_ISBN
    978-1-4244-9473-6
  • Electronic_ISBN
    0271-4302
  • Type

    conf

  • DOI
    10.1109/ISCAS.2011.5938156
  • Filename
    5938156