Title :
Estimating scatterer properties in rat fibroadenomas using various mathematical form factors
Author :
Hafez, Zachary T. ; Wirtzfeld, Lauren A. ; Battles, Andrew ; Miller, Rita J. ; Sarwate, Sandhya ; Oelze, Michael L. ; Hall, Timothy J. ; O´Brien, William D., Jr.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Illinois, Urbana, IL, USA
Abstract :
Quantitative ultrasound (QUS) imaging is a model-based approach aimed at lesion detection and classification. In this study, the RF backscattered signals from rat fibroadenomas were fit to various mathematical models to yield effective scatterer diameter (ESD) estimates which are tied to tissue microstructure. The goal of these experiments was to understand potential sources of scattering in live tissue across a wide frequency range and how results from different models compare to one another.
Keywords :
Gaussian distribution; backscatter; biomedical transducers; biomedical ultrasonics; cancer; physiological models; tumours; ultrasonic imaging; ultrasonic transducers; RF backscattered signals; Sprague Dawley rats; acini; effective scatterer diameter; fibroadenoma tumors; frequency 1.4 MHz to 18 MHz; glass bead; lesion detection; single-element transducers; size 1 cm to 6 cm; spherical Gaussian form factors; tissue microstructure; ultrasound imaging; Animals; Electrostatic discharge; Mathematical model; Microstructure; Neoplasms; RF signals; Radio frequency; Scattering; Ultrasonic imaging; Ultrasonic transducers;
Conference_Titel :
Ultrasonics Symposium (IUS), 2009 IEEE International
Conference_Location :
Rome
Print_ISBN :
978-1-4244-4389-5
Electronic_ISBN :
1948-5719
DOI :
10.1109/ULTSYM.2009.5441787
