Title :
Theoretical model for the threshold onset of contrast microbubble oscillations
Author :
Doinikov, Alexander A. ; Bouakaz, Ayache
Author_Institution :
INSERM U930 CNRS ERL 3106, Univ. Francois Rabelais, Tours, France
Abstract :
It has been reported recently through high speed optical observations of phospholipid-coated contrast microbubbles that there is a threshold value for the acoustic pressure amplitude below which the radial oscillation of the microbubbles does not occur. This paper suggests that the observed threshold behavior is a consequence of the fact that a phospholipid layer has a certain value of the limiting shear stress so that its deformation does not start until this limiting value is exceeded. A theoretical model is proposed for the description of this phenomenon. The model explains the experimentally observed dependence of the threshold onset of microbubble oscillation on the resting bubble radius.
Keywords :
biomedical ultrasonics; bubbles; nonlinear acoustics; radiation pressure; ultrasonic imaging; acoustic pressure amplitude threshold; contrast microbubble oscillation; limiting shear stress; microbubble deformation; microbubble radial oscillation; phospholipid coated contrast microbubbles; resting bubble radius; Acoustic signal detection; Elasticity; Encapsulation; Equations; Frequency; High speed optical techniques; Solids; Stress; Surface tension; Viscosity; limiting shear stress; microbubbles; pressure-dependent threshold behavior; ultrasound contrast agents;
Conference_Titel :
Ultrasonics Symposium (IUS), 2009 IEEE International
Conference_Location :
Rome
Print_ISBN :
978-1-4244-4389-5
Electronic_ISBN :
1948-5719
DOI :
10.1109/ULTSYM.2009.5442001