Mind-controlled micro-biomanipulation with position sensing feedback: System integration and validation

An integrated micro-biomanipulation system that can perform mind-controlled biomanipulation at micro scale is presented in the paper. The system incorporates a non-invasive electroencephalogram (EEG) device with a high-precision automated micromanipulator through high speed network. The human manipulation mind measured by the EEG can effectively drive the micromanipulator to perform the 2-D manipulation on bio-samples at micro scale. During the manipulation, the trace of human manipulation mind or movement signal is monitored by a custom-built high-precision position sensing detector (PSD) interface unit. In addition, topographical properties of all 14 EEG channels from the operator corresponding to 2-D mind movements are plotted and preliminarily analyzed. Experimental results validate the performance of the developed network-enabled and mind-controlled micro-biomanipulation system. Further work will focus on using the system to investigate neurobiofeedback mechanisms or manipulation behaviors of human brain during micro-biomanipulation and microassembly, so as to facilitate developing high-efficiency strategy of engineering approaches in micro/nano level.