DocumentCode :
2012230
Title :
Smart drug delivery using electrospun hollow nanofibers
Author :
Yang, Haifeng ; Dong, Liang
Author_Institution :
Iowa State Univ., Ames, IA, USA
fYear :
2010
fDate :
24-28 Jan. 2010
Firstpage :
308
Lastpage :
311
Abstract :
This paper report on a novel nano-electro-mechanical systems (NEMS) technology - nanoscale coaxial soft smart system (nCS3) that enables radial displacements of a multi-layered coaxial hollow fiber (CHF) and controlled modulations of a nanofluidic flow patterns inside the CHF responding to changes in local environments. The nCS3 has a unique nanostructure that consists of a liquid core and multiple layers of polymer and stimuli-responsive hydrogel. Smart and controlled release of drug molecules is realized using the nCS3.
Keywords :
drug delivery systems; hydrogels; nanobiotechnology; nanofibres; nanofluidics; polymers; NEMS technology; controlled modulations; drug molecules; multilayered coaxial electrospun hollow nanofiber; nanoelectromechanical systems technology; nanofluidic flow patterns; nanoscale coaxial soft smart system; polymer multiple layers; radial displacements; smart drug delivery; stimuli-responsive hydrogel; Biological control systems; Chemical technology; Coaxial components; Control systems; Displacement control; Drug delivery; Mesoporous materials; Nanobioscience; Pharmaceutical technology; Polymers;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2010 IEEE 23rd International Conference on
Conference_Location :
Wanchai, Hong Kong
ISSN :
1084-6999
Print_ISBN :
978-1-4244-5761-8
Electronic_ISBN :
1084-6999
Type :
conf
DOI :
10.1109/MEMSYS.2010.5442505
Filename :
5442505
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=2012230
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