DocumentCode
2034875
Title
Detecting immature precursor cells in pathological images of bone marrow based on morphology
Author
Li, Ling ; Cao, Guitao ; Shi, Jun ; Wu, Heng ; Zhang, Xianxia
Author_Institution
Software Eng. Inst., East China Normal Univ., Shanghai, China
Volume
5
fYear
2010
fDate
10-12 Aug. 2010
Firstpage
2190
Lastpage
2194
Abstract
It is an effective means for the early diagnosis of leukemia to study immature precursor cells in marrow pathological images by computer image processing technology. This paper proposed a new method about localization of immature precursor cells in Pathological images of bone marrow. Firstly, we use modified OSTU method to binarize the image; then we process the image with morphological operations, combined with their own characteristics and the sizes of cells; finally we obtain the right results of cellular localization. Experimental results show that the method proposed in this paper has a better performance on immature precursor cells identification, which addresses the problem unsolved in specific situation with general image segmentation methods. This lays a foundation for the future study in the area of distribution of cells.
Keywords
biology computing; bone; diseases; image segmentation; medical image processing; bone marrow; cellular localization; computer image processing; image segmentation; immature precursor cell identification; leukemia diagnosis; marrow pathological image; morphological operation; morphology; Bones; Image edge detection; Image segmentation; Morphology; Optimization; Pathology; Pixel; cell localization; immature precursor cells; marrow pathological image; morphology;
fLanguage
English
Publisher
ieee
Conference_Titel
Fuzzy Systems and Knowledge Discovery (FSKD), 2010 Seventh International Conference on
Conference_Location
Yantai, Shandong
Print_ISBN
978-1-4244-5931-5
Type
conf
DOI
10.1109/FSKD.2010.5569552
Filename
5569552
Link To Document