DocumentCode :
2034875
Title :
Detecting immature precursor cells in pathological images of bone marrow based on morphology
Author :
Li, Ling ; Cao, Guitao ; Shi, Jun ; Wu, Heng ; Zhang, Xianxia
Author_Institution :
Software Eng. Inst., East China Normal Univ., Shanghai, China
Volume :
5
fYear :
2010
fDate :
10-12 Aug. 2010
Firstpage :
2190
Lastpage :
2194
Abstract :
It is an effective means for the early diagnosis of leukemia to study immature precursor cells in marrow pathological images by computer image processing technology. This paper proposed a new method about localization of immature precursor cells in Pathological images of bone marrow. Firstly, we use modified OSTU method to binarize the image; then we process the image with morphological operations, combined with their own characteristics and the sizes of cells; finally we obtain the right results of cellular localization. Experimental results show that the method proposed in this paper has a better performance on immature precursor cells identification, which addresses the problem unsolved in specific situation with general image segmentation methods. This lays a foundation for the future study in the area of distribution of cells.
Keywords :
biology computing; bone; diseases; image segmentation; medical image processing; bone marrow; cellular localization; computer image processing; image segmentation; immature precursor cell identification; leukemia diagnosis; marrow pathological image; morphological operation; morphology; Bones; Image edge detection; Image segmentation; Morphology; Optimization; Pathology; Pixel; cell localization; immature precursor cells; marrow pathological image; morphology;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Fuzzy Systems and Knowledge Discovery (FSKD), 2010 Seventh International Conference on
Conference_Location :
Yantai, Shandong
Print_ISBN :
978-1-4244-5931-5
Type :
conf
DOI :
10.1109/FSKD.2010.5569552
Filename :
5569552
Link To Document :
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