Title :
Short-term QT variability: A marker for reduced repolarization reserve in anthracyclin therapy
Author :
Van Eck, H. J Ritsema ; Broeyer, F.J. ; van Herpen, G. ; Burggraaf, J. ; Kors, J.A.
Author_Institution :
Erasmus Med. Centre, Rotterdam, Netherlands
Abstract :
Using Fiducial Segment Averaging we measured the individual QT intervals in 5 minute recordings of patients on anthracyclin therapy. These intervals are used to calculate the short term QT-variability. The effect of anthracyclin therapy is seen in an increased variability together with an increased QTc interval both signifying a reduced repolarization reserve.
Keywords :
electrocardiography; medical computing; patient treatment; anthracyclin therapy; fiducial sgment averaging; human electrocardiogram; reduced repolarization reserve; short-term QT variability; Cardiology; Drugs; Electrocardiography; Heart rate; Heart rate interval; Humans; Measurement standards; Medical treatment; Myocardium; Safety;
Conference_Titel :
Computers in Cardiology, 2009
Conference_Location :
Park City, UT
Print_ISBN :
978-1-4244-7281-9
Electronic_ISBN :
0276-6547
