Title :
Constrained Nonlinear Estimation of FMRI Hemodynamic Response Parameters
Author :
Shi, Pengcheng ; Hu, Zhenghui
Author_Institution :
Hong Kong Univ. of Sci. & Technol., Hong Kong
fDate :
Sept. 16 2007-Oct. 19 2007
Abstract :
We present a constrained nonlinear optimization approach to the estimation of hemodynamic response (HR) shape from fMRI images. The controlled random search (CRS) based strategy limits the HR parameters within a physically/physiologically plausible phase space, and thus may produce more meaningful results than the traditional unconstrained methods. Block-design and event-related fMRI experiments have been conducted to examine the validity of the framework.
Keywords :
biomedical MRI; haemodynamics; nonlinear estimation; phase space methods; CRS; constrained nonlinear estimation; controlled random search; fMRI hemodynamic response parameter; functional magnetic resonance imaging; physically-physiologically plausible phase space; Biomedical computing; Biomedical imaging; Constraint optimization; Convergence; Hemodynamics; Parameter estimation; Parametric statistics; Physics computing; Shape; Statistical analysis; controlled random search; hemodynamic response; optimization;
Conference_Titel :
Image Processing, 2007. ICIP 2007. IEEE International Conference on
Conference_Location :
San Antonio, TX
Print_ISBN :
978-1-4244-1437-6
Electronic_ISBN :
1522-4880
DOI :
10.1109/ICIP.2007.4379874
