• DocumentCode
    2050035
  • Title

    Constrained Nonlinear Estimation of FMRI Hemodynamic Response Parameters

  • Author

    Shi, Pengcheng ; Hu, Zhenghui

  • Author_Institution
    Hong Kong Univ. of Sci. & Technol., Hong Kong
  • Volume
    5
  • fYear
    2007
  • fDate
    Sept. 16 2007-Oct. 19 2007
  • Abstract
    We present a constrained nonlinear optimization approach to the estimation of hemodynamic response (HR) shape from fMRI images. The controlled random search (CRS) based strategy limits the HR parameters within a physically/physiologically plausible phase space, and thus may produce more meaningful results than the traditional unconstrained methods. Block-design and event-related fMRI experiments have been conducted to examine the validity of the framework.
  • Keywords
    biomedical MRI; haemodynamics; nonlinear estimation; phase space methods; CRS; constrained nonlinear estimation; controlled random search; fMRI hemodynamic response parameter; functional magnetic resonance imaging; physically-physiologically plausible phase space; Biomedical computing; Biomedical imaging; Constraint optimization; Convergence; Hemodynamics; Parameter estimation; Parametric statistics; Physics computing; Shape; Statistical analysis; controlled random search; hemodynamic response; optimization;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Image Processing, 2007. ICIP 2007. IEEE International Conference on
  • Conference_Location
    San Antonio, TX
  • ISSN
    1522-4880
  • Print_ISBN
    978-1-4244-1437-6
  • Electronic_ISBN
    1522-4880
  • Type

    conf

  • DOI
    10.1109/ICIP.2007.4379874
  • Filename
    4379874