Title :
Autism: A Systems Biology Disease
Author :
Randolph-Gips, Mary
Author_Institution :
Syst. & Comput. Eng., Univ. of Houston-Clear Lake, Houston, TX, USA
Abstract :
Autism is the fastest growing developmental disorder in the world today. People with autism present with stereotypy and with social and communication impairments. Research has shown that autism has roots in many systems in the body, including the metabolic, mitochondrial, immunological, gastrointestinal and the neurological. These systems interact in complex and highly interdependent ways. Autism poses a rich test bed for systems biology modeling techniques. This paper reviews some of the systems disturbed in autism and suggests several systems biology research areas.
Keywords :
cellular biophysics; diseases; molecular biophysics; neurophysiology; autism; communication impairments; developmental disorder; disease; gastrointestinal system; immunological system; metabolic system; mitochondrial system; neurological system; social impairments; stereotypy; systems biology modeling techniques; Autism; Biochemistry; Gastrointestinal tract; Genetics; Immune system; Stress; autism; gastrointestinal; immune; metabolic; modeling; neurological; oxidative stress; systems biology;
Conference_Titel :
Healthcare Informatics, Imaging and Systems Biology (HISB), 2011 First IEEE International Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-4577-0325-6
Electronic_ISBN :
978-0-7695-4407-6
DOI :
10.1109/HISB.2011.13
