• DocumentCode
    2062616
  • Title

    GenDiv - A Hardware Algorithm for Intron and Exon String Detection in DNA Chains

  • Author

    Cret, Octavian ; Marginean, S. ; Lelutiu, C. ; Mathe, Z.

  • Author_Institution
    Tech. Univ., Cluj-Napoca
  • fYear
    2007
  • fDate
    27-29 Aug. 2007
  • Firstpage
    260
  • Lastpage
    266
  • Abstract
    This paper introduces an algorithm for DNA string detection and proposes its efficient hardware implementation on FPGA devices. Its main application field is intended to be the detection of intron and exon strings in DNA chains, but its applicability is not limited to Genetics. The GenDiv algorithm is based on the dynamic programming method. For the software implementation, the algorithm´s complexity is O(mldrn), where m and n; are the sizes of the two DNA strings being processed; in hardware, after a few adaptations that are presented, the algorithm can be implemented in a systolic array and its running time becomes linear O(m+n). Simultaneously, the necessary circuitry resources in the FPGA chip are also showing a linear trade-off. The simulations and tests that have been run show a gain of speed of several orders of magnitude of the hardware implementation over the software one.
  • Keywords
    biocomputing; dynamic programming; field programmable gate arrays; DNA chains; FPGA chip; FPGA devices; GenDiv algorithm; dynamic programming method; exon string detection; hardware algorithm; hardware implementation; intron string detection; Application software; Circuit simulation; Circuit testing; DNA; Dynamic programming; Field programmable gate arrays; Genetics; Hardware; Software algorithms; Systolic arrays;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Field Programmable Logic and Applications, 2007. FPL 2007. International Conference on
  • Conference_Location
    Amsterdam
  • Print_ISBN
    978-1-4244-1060-6
  • Electronic_ISBN
    978-1-4244-1060-6
  • Type

    conf

  • DOI
    10.1109/FPL.2007.4380657
  • Filename
    4380657