Title :
Medical applications of radiation micro-force
Author :
Fatemi, Mostafa ; Greenleaf, James F.
Author_Institution :
Mayo Clinic, Rochester, MN, USA
Abstract :
The general direction of this research is measurement of sound and vibration in response to a micro-force. The main hypothesis is that by measuring the sound and/or vibration resulting from such small forces we will be able to obtain important information about the object. The micro-force, which is in mN range, is produced by the radiation force of ultrasound, and the resulting vibration is in nanometer or angstrom range. The stress field is confined to a small region with a few hundred microns in diameter. We have shown that by measuring the acoustic field resulting from such vibrations, which are in low (kHz) frequency range, we can estimate some of the mechanical properties of objects. We have also used this method to image tissue at high resolutions and detect small particles. This imaging technology promises a wide range of medical applications, including imaging organs, detection of arterial calcifications and breast microcalcifications, and evaluation of the structural integrity of implants
Keywords :
biomechanics; biomedical measurement; biomedical ultrasonics; ultrasonic measurement; vibration measurement; acoustic field; arterial calcification detection; breast microcalcification detection; implant structural integrity; mechanical properties; medical applications; organ imaging; radiation micro-force; small particle detection; sound measurement; stress field; tissue imaging; ultrasound; vibration measurement; Acoustic imaging; Biomedical equipment; Force measurement; Frequency estimation; High-resolution imaging; Medical services; Stress; Ultrasonic imaging; Ultrasonic variables measurement; Vibration measurement;
Conference_Titel :
Bioinformatics and Bioengineering Conference, 2001. Proceedings of the IEEE 2nd International Symposium on
Conference_Location :
Bethesda, MD
Print_ISBN :
0-7695-1423-5
DOI :
10.1109/BIBE.2001.974438