Title :
Detection of biomolecules using In2O3 nanowires
Author :
Li, Chao ; Zhang, Daihua ; Lei, Bo ; Zhou, Chongwu
Author_Institution :
Dept. of Electr. Eng., Southern California Univ., Los Angeles, CA, USA
Abstract :
In2O3 nanowire transistors have been used to detect low-density lipoprotein (LDL) cholesterol, which is the major carrier of cholesterol in blood and the offending agent in coronary heart diseases. Enhanced conductance was observed when the device was exposed to LDL, as well as a negative shift of gate threshold voltage. These phenomena can be explained by the chemical gating effect of LDL molecules to In2O3 nanowires.
Keywords :
biosensors; electrical conductivity; field effect transistors; indium compounds; macromolecules; nanowires; proteins; In2O3; In2O3 nanowire transistors; biomolecules detection; blood; chemical gating effect; coronary heart diseases; gate threshold voltage; low density lipoprotein cholesterol; Blood; Cardiac disease; Chemicals; Electrodes; FETs; Molecular biophysics; Nanomaterials; Nanowires; Scanning electron microscopy; Threshold voltage;
Conference_Titel :
Nanotechnology, 2003. IEEE-NANO 2003. 2003 Third IEEE Conference on
Print_ISBN :
0-7803-7976-4
DOI :
10.1109/NANO.2003.1231798
