Design and implementation of a DNA Sequence Processor

Author

Dimidis, Stamatis E. ; Kamel, Nabil N. ; Dame, John B.

Author_Institution

Database Syst. Res. & Dev. Center, Florida Univ., Gainesville, FL, USA

Volume

5

fYear

1994

fDate

4-7 Jan. 1994

Firstpage

98

Lastpage

107

Abstract

The DNA Sequence Processor (SP) is a tool developed as an aid to the Malaria Genome Project at the University of Florida, as well as for any other large sequencing project conducted in a centralized multiuser DNA sequencing facility. The tool accepts sequences of DNA fragments, determined using an automated DNA sequencing machine, and processes them based on certain rules and parameters as specified by human experts. A remote service termed the Basic Local Alignment Search Tool (BLAST) was utilized by SP. SP performs several bookkeeping and project management functions, and generates a number of useful reports that can be viewed through a user-friendly graphical interface. Assets of SP include the classification of rejected sequences according to the reason for their rejection, and the creation of detailed logs documenting every step in processing each sequence.<>

Keywords

DNA; biology computing; graphical user interfaces; project management; special purpose computers; BLAST; Basic Local Alignment Search Tool; DNA Sequence Processor; DNA fragments; Malaria Genome Project; automated DNA sequencing machine; bookkeeping functions; centralized multiuser DNA sequencing facility; documentation; logging; project management functions; rejected sequence classification; remote service; report generation; user-friendly graphical interface;

fLanguage

English

Publisher

ieee

Conference_Titel

System Sciences, 1994. Proceedings of the Twenty-Seventh Hawaii International Conference on

Conference_Location

Wailea, HI, USA

Print_ISBN

0-8186-5090-7

Type

conf

DOI

10.1109/HICSS.1994.323584

Filename

323584