DocumentCode
2076106
Title
Single-cell detection and classification in phase contrast images
Author
Athelogou, M. ; Eblenkamp, M. ; Schmidt, G. ; Novotny, F. ; Wintermantel, E. ; Binnig, G.
Author_Institution
Definiens AG, Munich, Germany
fYear
2010
fDate
3-5 Nov. 2010
Firstpage
1
Lastpage
4
Abstract
This paper presents a method for the fully automated segmentation, classification and quantification of the morphology of individual cells in phase-contrast images. We utilize this method to calculate automatically the confluence of the corresponding cell culture and to quantify the degree of toxic damage of each individual cell after phenol incubation. These results are compared to standard cytotoxicity assays.
Keywords
cellular biophysics; image classification; image segmentation; medical image processing; cell classification; cell culture; cell morphology; cytotoxicity assay; fully automated segmentation; phase contrast image; single cell detection; Biology; Biomedical imaging; Image segmentation; Phase measurement;
fLanguage
English
Publisher
ieee
Conference_Titel
Information Technology and Applications in Biomedicine (ITAB), 2010 10th IEEE International Conference on
Conference_Location
Corfu
Print_ISBN
978-1-4244-6559-0
Type
conf
DOI
10.1109/ITAB.2010.5687789
Filename
5687789
Link To Document