Optimization method research of Simulated Moving Bed process

The Simulated Moving Bed (SMB) chromatography has been used extensively for the complex separation tasks in the areas of petroleum chemicals, fine chemicals, pharmaceuticals, and food processing in recent years as a main modern separation technology. The steady state optimization problem of the Simulated Moving Bed chromatographic separation process is studied when the material properties, the zone and the column configuration are determined and optimization strategy based on the triangle theory are proposed. The validity of the optimization strategy is confirmed through simulation.