Title :
Model predictive control of blood glucose in type I diabetics using subcutaneous glucose measurements
Author :
Lynch, Sandra M. ; Bequette, B. Wayne
Author_Institution :
Isermann Dept. of Chem. Eng., Rensselaer Polytech. Inst., Troy, NY, USA
Abstract :
A constrained model predictive controller is implemented on a simulated type I diabetic patient. A Kalman filter is used to estimate the blood glucose concentration based on a subcutaneous glucose measurement. The model predictive controller returns blood glucose to normoglycemic ranges when subjected to a meal disturbance. The settling time is similar to that of a non-diabetic.
Keywords :
Kalman filters; blood; diseases; filtering theory; physiological models; predictive control; Kalman filter; blood glucose concentration estimation; constrained model predictive controller; diabetes mellitus; meal disturbance; normoglycemic ranges; settling time; subcutaneous glucose measurements; type I diabetics; Blood; Diabetes; Equations; Insulin; Medical treatment; Open loop systems; Pancreas; Predictive control; Predictive models; Sugar;
Conference_Titel :
American Control Conference, 2002. Proceedings of the 2002
Print_ISBN :
0-7803-7298-0
DOI :
10.1109/ACC.2002.1024561
