Title :
Application of three dimensional image analysis to the mammalian cell nucleus
Author :
Samarabandu, J. ; Cheng, P.C. ; Berezney, R.
Author_Institution :
Dept. of Biophys. Sci., State Univ. of New York, Buffalo, NY, USA
Abstract :
A three dimensional image segmentation and analysis system is proposed to study the confocal microscopy images of DNA replication sites in cell nuclei. The algorithm presented here includes detection of replication sites in 2D slices in the image and reconstructing 3D objects from 2D data. We also present a user interface to allow easy interaction with both the segmentation algorithm and the 3D segmented data
Keywords :
DNA; biology computing; image reconstruction; image segmentation; medical image processing; user interfaces; 2D data; 2D slices; 3D object reconstruction; 3D segmented data; DNA replication sites; cell nuclei; confocal microscopy images; mammalian cell nucleus; replication site detection; segmentation algorithm; three dimensional image analysis; three dimensional image segmentation; user interface; Biology; Cells (biology); DNA; Data mining; Fibroblasts; Image analysis; Image segmentation; Mice; Microscopy; Pattern analysis;
Conference_Titel :
Southeastcon '94. Creative Technology Transfer - A Global Affair., Proceedings of the 1994 IEEE
Conference_Location :
Miami, FL
Print_ISBN :
0-7803-1797-1
DOI :
10.1109/SECON.1994.324274
