• DocumentCode
    2091633
  • Title

    Study on effects of two kinds of cactus polysaccharides on the protein contents and the lipid fluidity of erythrocyte membrane in S180 mice

  • Author

    Chenfeng, Ji ; Yubin, Ji ; Xiang, Zou

  • Author_Institution
    Harbin Univ. of Commerce, Harbin
  • fYear
    2007
  • fDate
    23-27 May 2007
  • Firstpage
    1685
  • Lastpage
    1688
  • Abstract
    To study the effects of two kinds of cactus polysaccharides on band 3 protein content, cross-linking protein content, and the lipid fluidity of erythrocyte membrane in S180 mice. Membrane protein content is analyzed by SDS-PAGE, and lipid fluidity of the membrane is measured by the Skinitzky method. The two kinds of cactus polysaccharide increase the content of band 3 protein, decrease the content of cross-linking protein, and increase lipid fluidity. For medical cactus polysaccharide, the effect of the medium dosage group is significant (P><0.01); but for edible cactus polysaccharide, it is the high dosage group that has a significant effect (P<0.01). By improving the functioning of erythrocyte membrane of tumor-bearing mice, the two kinds of cactus polysaccharides enhance their immunological function, and this may be one of the anti-tumor mechanisms of cactus polysaccharides.
  • Keywords
    biochemistry; biomembranes; cancer; cellular biophysics; drugs; lipid bilayers; molecular biophysics; proteins; tumours; S180 mice; SDS-PAGE; Skinitzky method; antitumor mechanism; cactus polysaccharides effects; cross-linking protein; dosage; erythrocyte membrane; immunological function; lipid fluidity; protein contents; tumor-bearing mice; Animals; Biomedical imaging; Biomembranes; Buffer storage; Instruments; Lipidomics; Mice; Neoplasms; Pharmaceuticals; Proteins; band 3 protein; cactus; cross-linking protein; lipid fluidity; polysaccharide;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Complex Medical Engineering, 2007. CME 2007. IEEE/ICME International Conference on
  • Conference_Location
    Beijing
  • Print_ISBN
    978-1-4244-1077-4
  • Electronic_ISBN
    978-1-4244-1078-1
  • Type

    conf

  • DOI
    10.1109/ICCME.2007.4382034
  • Filename
    4382034