Title :
An analog circuit implementation of a Huber-Braun cold receptor neuron model
Author :
Hermida, R. ; Patrone, M. ; Pijuan, M. ; Monzon, P. ; Oreggioni, Julian
Author_Institution :
Fac. de Ingeniera, Univ. de la Republica, Montevideo, Uruguay
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
We present the design and implementation of an electronic device that, using off the shelf discrete analog components, implements the mathematical model of a cold receptor neuron called Huber-Braun. This model describes the electrical behavior of certain kinds of receptors when interacting with their environment, and it consists of a set of differential equations that has only been solved by numeric simulations. By these means a chaotic behavior has been found. An analog computer can be relevant for further analysis and validation of the model. The results obtained by means of numeric simulations and through our analog circuit simulator are consistent. In particular, temperature and external current bifurcation diagrams were successfully built. Finally, the electronic device allows the observation of all relevant variables and most of the expected behavior (tonic firing, chaotic, burst discharge, subthreshold oscillation and steady state).
Keywords :
analogue circuits; analogue computers; bifurcation; biochemistry; bioelectric phenomena; biomembranes; cellular biophysics; chaos; differential equations; neural nets; numerical analysis; physiological models; Huber-Braun cold receptor neuron model; analog circuit implementation; analog circuit simulator; analog computer; chaotic behavior; differential equations; electrical behavior; electronic device; external current bifurcation diagrams; mathematical model; numeric simulation; shelf discrete analog components; temperature current bifurcation diagrams; Bifurcation; Biological system modeling; Integrated circuit modeling; Mathematical model; Neurons; Numerical models; Oscillators; Ion Channels; Membrane Potentials; Models, Neurological; Neurons; Nonlinear Dynamics;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6346689