• DocumentCode
    2098525
  • Title

    Interaction of skin tissue with nanosecond pulsed laser-induced stress wave used for gene transfection

  • Author

    Sato, Shunichi ; Terakawa, Mitsuhiro ; Takano, Shinta ; Tsuda, Hitoshi ; Ashida, Hiroshi ; Okano, Hideyuki ; Obara, Minoru

  • Author_Institution
    Nat. Defense Med. Coll. Res. Inst., Saitama
  • fYear
    2007
  • fDate
    21-25 Oct. 2007
  • Firstpage
    155
  • Lastpage
    156
  • Abstract
    In the skin exposed to laser-induced stress wave (LISW), tissue alteration was limited under the optimum conditions for transfection. Efficient gene expression observed in a "LISW first" delivery mode suggests a new mechanism for transfection.
  • Keywords
    biological effects of laser radiation; biomedical equipment; cellular biophysics; delivery mode; gene expression; gene transfection; nanosecond pulsed laser-induced stress wave; skin tissue; Chemical lasers; DNA; Educational institutions; Gene expression; Laser theory; Optical pulses; Proteins; Skin; Space vector pulse width modulation; Stress;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics Society, 2007. LEOS 2007. The 20th Annual Meeting of the IEEE
  • Conference_Location
    Lake Buena Vista, FL
  • ISSN
    1092-8081
  • Print_ISBN
    978-1-4244-0925-9
  • Electronic_ISBN
    1092-8081
  • Type

    conf

  • DOI
    10.1109/LEOS.2007.4382323
  • Filename
    4382323