Title :
A High-Speed Method of Identifying Conserved Residues
Author :
Guo, Junen ; Li, Jingxiu ; Shu, Yunxing
Author_Institution :
Dept. of Comput. & Inf. Eng., Luoyang Inst. of Sci. & Technol., Luoyang, China
Abstract :
The conserved residues, which are comparatively stable in the process of biological evolvement, are significant to the study of the structure and function of protein. Therefore, identifying conserved residues will greatly stimulate the development of bioinformatics. Based on biochemical, geometric and dynamic features of the amino acids, this paper proposes a high-speed algorithm to rapidly identify conserved residues in protein. The results of experiments indicate that compared with other similar algorithm, this algorithm can identify the conserved residues in protease families more rapidly.
Keywords :
bioinformatics; proteins; bioinformatics development; biological evolvement; conserved residues; protease families; protein data bank; Amino acids; Biochemistry; Bioinformatics; Biology computing; Data mining; Feature extraction; Information retrieval; Iterative algorithms; Protein engineering; Sequences;
Conference_Titel :
Biomedical Engineering and Informatics, 2009. BMEI '09. 2nd International Conference on
Conference_Location :
Tianjin
Print_ISBN :
978-1-4244-4132-7
Electronic_ISBN :
978-1-4244-4134-1
DOI :
10.1109/BMEI.2009.5302145