DocumentCode
2103925
Title
Label-free, single molecule detection of cytokines using optical microcavities
Author
Armani, Andrea M. ; Fraser, Scott E. ; Vahala, Kerry J.
Author_Institution
California Inst. of Technol., Pasadena
fYear
2007
fDate
21-25 Oct. 2007
Firstpage
596
Lastpage
597
Abstract
Interleukin-2 (IL2) is a cytokine that regulates T-cell growth and is used in cancer therapies. By sensitizing a microcavity sensor surface with anti-IL2 and monitoring the resonant frequency, single molecules of IL2 can be detected.
Keywords
biological techniques; cancer; cellular biophysics; microcavities; microsensors; molecular biophysics; optical sensors; proteins; T-cell growth; cancer therapies; cytokines; interleukin-2; microcavity sensor; optical microcavities; resonant frequency; single molecule detection; Biomedical optical imaging; Microcavities; Optical refraction; Optical resonators; Optical sensors; Optical surface waves; Optical variables control; Optical waveguides; Resonance; Sensor arrays;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics Society, 2007. LEOS 2007. The 20th Annual Meeting of the IEEE
Conference_Location
Lake Buena Vista, FL
ISSN
1092-8081
Print_ISBN
978-1-4244-0925-9
Electronic_ISBN
1092-8081
Type
conf
DOI
10.1109/LEOS.2007.4382547
Filename
4382547
Link To Document