Title :
Parameter estimation of the Huxley cross-bridge muscle model in humans
Author :
Vardy, A.N. ; de Vlugt, E. ; van der Helm, Frans C. T.
Author_Institution :
Dept. of Biomech. Eng., Delft Univ. of Technol., Delft, Netherlands
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
The Huxley model has the potential to provide more accurate muscle dynamics while affording a physiological interpretation at cross-bridge level. By perturbing the wrist at different velocities and initial force levels, reliable Huxley model parameters were estimated in humans in vivo using a Huxley muscle-tendon complex. We conclude that these estimates may be used to investigate and monitor changes in microscopic elements of muscle functioning from experiments at joint level.
Keywords :
biomechanics; electromyography; parameter estimation; perturbation theory; Huxley cross-bridge muscle model; Huxley muscle-tendon complex; electromyograms; initial force levels; joint level; microscopic elements; muscle dynamics; muscle functioning; parameter estimation; perturbation; physiological interpretation; velocity; wrist; Biological system modeling; Biomechanics; In vivo; Joints; Muscles; Tendons; Wrist; Algorithms; Computer Simulation; Female; Humans; Male; Models, Biological; Muscle Contraction; Muscle, Skeletal; Range of Motion, Articular; Tendons; Wrist Joint;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6347074
