DocumentCode
2106992
Title
Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe
Author
Hara, S.A. ; Kim, B.J. ; Kuo, Jonathan T. W. ; Lee, Chi-Kwan ; Gutierrez, C.A. ; Tuan Hoang ; Meng, Ellis
Author_Institution
Dept. of Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
fYear
2012
fDate
Aug. 28 2012-Sept. 1 2012
Firstpage
5126
Lastpage
5129
Abstract
We present the preliminary electrochemical characterization of 3D Parylene C sheath microelectrode array probes towards realizing reliable chronic neuroprosthetic recordings. Electrochemical techniques were used to verify electrode integrity after our novel post-fabrication thermoforming process was applied to flat surface micromachined structures to achieve a hollow sheath probe shape. Characterization of subsequent neurotrophic coatings was performed and accelerated life testing was used to simulate six months in vivo. Prior to probe implantation, crosstalk was measured and electrode surface properties were evaluated through the use of electrochemical impedance spectroscopy.
Keywords
bioelectric phenomena; biomedical electrodes; biomedical materials; electrochemical electrodes; electrochemical impedance spectroscopy; microelectrodes; micromachining; neurophysiology; polymer films; prosthetics; thermoforming; accelerated life testing; electrochemical impedance spectroscopy; electrode integrity; electrode surface properties; flat surface micromachined structures; hollow sheath probe shape; novel post-fabrication thermoforming process; parylene C sheath microelectrode array probe; preimplantation electrochemical characterization; reliable chronic neuroprosthetic recordings; subsequent neurotrophic coatings; time 6 month; Biomedical measurements; Coatings; Crosstalk; Microelectrodes; Probes; Surface impedance; Coated Materials, Biocompatible; Electric Impedance; Electrochemistry; Electrodes, Implanted; Equipment Design; Equipment Failure Analysis; Materials Testing; Microelectrodes; Polymers; Prosthesis Implantation; Reproducibility of Results; Sensitivity and Specificity; Xylenes;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location
San Diego, CA
ISSN
1557-170X
Print_ISBN
978-1-4244-4119-8
Electronic_ISBN
1557-170X
Type
conf
DOI
10.1109/EMBC.2012.6347147
Filename
6347147
Link To Document