DocumentCode :
2106992
Title :
Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe
Author :
Hara, S.A. ; Kim, B.J. ; Kuo, Jonathan T. W. ; Lee, Chi-Kwan ; Gutierrez, C.A. ; Tuan Hoang ; Meng, Ellis
Author_Institution :
Dept. of Biomed. Eng., Univ. of Southern California, Los Angeles, CA, USA
fYear :
2012
fDate :
Aug. 28 2012-Sept. 1 2012
Firstpage :
5126
Lastpage :
5129
Abstract :
We present the preliminary electrochemical characterization of 3D Parylene C sheath microelectrode array probes towards realizing reliable chronic neuroprosthetic recordings. Electrochemical techniques were used to verify electrode integrity after our novel post-fabrication thermoforming process was applied to flat surface micromachined structures to achieve a hollow sheath probe shape. Characterization of subsequent neurotrophic coatings was performed and accelerated life testing was used to simulate six months in vivo. Prior to probe implantation, crosstalk was measured and electrode surface properties were evaluated through the use of electrochemical impedance spectroscopy.
Keywords :
bioelectric phenomena; biomedical electrodes; biomedical materials; electrochemical electrodes; electrochemical impedance spectroscopy; microelectrodes; micromachining; neurophysiology; polymer films; prosthetics; thermoforming; accelerated life testing; electrochemical impedance spectroscopy; electrode integrity; electrode surface properties; flat surface micromachined structures; hollow sheath probe shape; novel post-fabrication thermoforming process; parylene C sheath microelectrode array probe; preimplantation electrochemical characterization; reliable chronic neuroprosthetic recordings; subsequent neurotrophic coatings; time 6 month; Biomedical measurements; Coatings; Crosstalk; Microelectrodes; Probes; Surface impedance; Coated Materials, Biocompatible; Electric Impedance; Electrochemistry; Electrodes, Implanted; Equipment Design; Equipment Failure Analysis; Materials Testing; Microelectrodes; Polymers; Prosthesis Implantation; Reproducibility of Results; Sensitivity and Specificity; Xylenes;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
ISSN :
1557-170X
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
Type :
conf
DOI :
10.1109/EMBC.2012.6347147
Filename :
6347147
Link To Document :
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