Title :
Nonlinear mechanics of DNA doule strand: existence of the compact-envelope bright solitary wave
Author :
Ndjoko, P.B. ; Bilbault, J. ; Binczak, S. ; Kofane, Temoleon Crepin
Author_Institution :
LE2I Lab., Univ. of Burgundy, Dijon, France
fDate :
Aug. 28 2012-Sept. 1 2012
Abstract :
We study the nonlinear dynamics of a homogeneous DNA chain which is based on site-dependent finite stacking and pairing enthalpies. We introduce an extended nonlinear Schrödinger equation describing the dynamics of modulated wave in DNA model. We obtain envelope bright solitary waves with compact support as a solution. Analytical criteria of existence of this solution are derived. The stability of bright compactons is confirmed by numerical simulations of the exact equations of the lattice. The impact of the finite stacking energy is investigated and we show that some of these compact bright solitary waves are robust, while others decompose very quickly depending on the finite stacking parameters.
Keywords :
DNA; Schrodinger equation; functional analysis; molecular biophysics; molecular configurations; nonlinear dynamical systems; compact-envelope bright solitary wave; extended nonlinear Schrodinger equation; finite stacking energy; finite stacking enthalpy; homogeneous DNA chain; modulated wave; nonlinear dynamics; nonlinear mechanics; pairing enthalpy; DNA; Equations; Lattices; Mathematical model; Numerical stability; Stability analysis; Stacking; DNA; Models, Molecular; Nonlinear Dynamics; Nucleic Acid Conformation;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4244-4119-8
Electronic_ISBN :
1557-170X
DOI :
10.1109/EMBC.2012.6347222