• DocumentCode
    2116445
  • Title

    A personalized mitral valve closure simulator

  • Author

    Burlina, Philippe ; Mukherjee, Rohan ; Sprouse, C.

  • Author_Institution
    Appl. Phys. Lab., Johns Hopkins Univ., Laurel, MD, USA
  • fYear
    2012
  • fDate
    Aug. 28 2012-Sept. 1 2012
  • Firstpage
    6636
  • Lastpage
    6640
  • Abstract
    We describe a method for performing modeling and simulation to predict the closure of the Mitral Valve (MV) using patient specific anatomical information derived from 3D Transesophageal Echocardiography (3D TEE). The ability to predict the MV closure behavior is an important step along the way of developing personalized simulation tools that would allow a surgeon to perform preoperative planning and decide between various MV repair options. While the MV is an important use case because of its relevance and prevalence among reconstructive cardiac interventions, the study described here can provide a blueprint to perform pre-operative planning for other cardiac surgical interventions. The method reported here exploits the Saint Venant-Kirchhoff elasticity model that is tuned to match empirical observations of the MV strainstress behavior. Using intraoperative 3D TEE data, the proposed simulator was evaluated over 10 test cases and resulted in mean prediction absolute error values of 1.81 mm.
  • Keywords
    biomechanics; echocardiography; elasticity; physiological models; stress-strain relations; surgery; 3D transesophageal echocardiography; MV closure behavior; MV repair; MV strain-stress behavior; Saint Venant-Kirchhoff elasticity model; cardiac surgical interventions; empirical observations; intraoperative 3D TEE data; patient specific anatomical information; personalized mitral valve closure simulator; personalized simulation tools; preoperative planning; reconstructive cardiac interventions; surgeon; Computational modeling; Heart; Predictive models; Strain; Stress; Surgery; Valves; Algorithms; Cardiac Surgical Procedures; Computer Simulation; Echocardiography, Three-Dimensional; Echocardiography, Transesophageal; Heart; Humans; Linear Models; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Prolapse; Models, Cardiovascular; Reproducibility of Results; Surgery, Computer-Assisted;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE
  • Conference_Location
    San Diego, CA
  • ISSN
    1557-170X
  • Print_ISBN
    978-1-4244-4119-8
  • Electronic_ISBN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/EMBC.2012.6347516
  • Filename
    6347516