Cantilever-type electrode array based sorting system

Author

Kim, Youngho ; Lee, Junghun ; Kim, Byungkyu ; Park, Seokho

Author_Institution

Robot. Res. Center, Korea Aerosp. Univ. (KAU), Goyang, South Korea

fYear

2010

fDate

1-4 Nov. 2010

Firstpage

1914

Lastpage

1917

Abstract

We present cantilever-type electrode (CE) array based sorting system, which is comprised of three parts such as CE array, separation module, and container for vertical pool. In order to sort target particles with different physical and dielectric material property, negative dielectrophoretic (n-DEP) force due to electric field generated from cantilever-type electrode is employed. The direction of particles on CE array is determined by summation vector among gravitation, hydrodynamic force and n-DEP force acting on particles. By using blood sample including human breast cancer cells (MCF 7s), we demonstrate that this system is applicable to separate MCF 7 cells under the condition of low voltage (lOVp-p with 500 KHz) and flow rate of 20μL/min due to draining of vertical pool.

Keywords

bioelectric phenomena; biomedical electrodes; cancer; cellular biophysics; dielectric properties; electrophoresis; CE array; MCF 7s; blood sample; cantilever-type electrode array based sorting system; dielectric material property; electric field generation; gravitation; human breast cancer cells; hydrodynamic force; n-DEP force; negative dielectrophoretic force; particle sorting; separation module; summation vector; vertical pool container;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2010 IEEE

Conference_Location

Kona, HI

ISSN

1930-0395

Print_ISBN

978-1-4244-8170-5

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2010.5690014

Filename

5690014