Simulation study of the effect of modelling errors on the solution of inverse cardiac source imaging problem using realistic source patterns

Author

Skipa, O. ; Sachse, FB ; Werner, CD ; Dössel, O.

Author_Institution

Inst. fur Biomedizinische Technik, Karlsruhe Univ., Germany

fYear

2001

fDate

2001

Firstpage

41

Lastpage

44

Abstract

The effect of the modelling errors on the solution of the inverse problem of electrocardiography is investigated. The electrocardiographic signal is simulated using a finite element model of the human torso and realistic source patterns gained with a cellular automaton. Noise is added to simulated measurements and the inverse problem is solved. The modelling errors consist of false conductivity assumptions, changed anisotropy ratio of skeletal muscles and geometric errors. The effect of modelling errors on optimal regularization parameter determination is investigated. The changes in muscle anisotropy and heart position are shown to have the highest effect on reconstructed epicardial potentials. CRESO (Composite REsidual and Smoothing Operator) and L-curve criteria for optimal regularization parameter estimation are compared

Keywords

bioelectric potentials; biomedical imaging; cellular automata; electrical conductivity; electrocardiography; errors; finite element analysis; inverse problems; muscle; parameter estimation; physiological models; signal sources; simulation; CRESO criteria; L-curve criteria; anisotropy ratio; cellular automaton; composite residual/smoothing operator; electrocardiographic signal simulation; false conductivity assumptions; finite element model; geometric errors; heart position; human torso; inverse cardiac source imaging problem; modelling errors; muscle anisotropy; noise; optimal regularization parameter determination; reconstructed epicardial potentials; simulated measurements; skeletal muscles; source patterns; Anisotropic magnetoresistance; Automata; Electrocardiography; Finite element methods; Humans; Inverse problems; Muscles; Noise measurement; Solid modeling; Torso;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 2001

Conference_Location

Rotterdam

ISSN

0276-6547

Print_ISBN

0-7803-7266-2

Type

conf

DOI

10.1109/CIC.2001.977586

Filename

977586