Title :
High sensitive circular Hall Effect sensor for magnetic bead labeled immunoassay
Author :
Zhang, Bowei ; Korman, Can E. ; Zaghloul, Mona E.
Author_Institution :
Inst. of MEMS &VLSI Technol., George Washington Univ., Washington,DC USA
Abstract :
A novel circular shape CMOS Hall Effect sensor design is proposed in this paper. Compared with traditional rectangular shape Hall Effect sensor, the proposed design can improve the sensitivity significantly. By implementing this sensor design with readout circuit, amplifier and DSP circuit in a CMOS chip, the Enzyme-Linked Immunosorbent Assay (ELISA) can be replaced by a lower cost, more portable and higher sensitive magnetic bead labeled immunoassay platform, which could eventually realize molecular diagnosis on chip.
Keywords :
CMOS integrated circuits; Hall effect; biomedical electronics; biosensors; enzymes; magnetic sensors; DSP circuit; ELISA; Enzyme-Linked Immunosorbent Assay; amplifier; circular shape CMOS Hall effect sensor design; high sensitive circular Hall effect sensor; magnetic bead labeled immunoassay; molecular diagnosis; readout circuit; CMOS integrated circuits; CMOS technology; Hall effect; Magnetic fields; Magnetic resonance imaging; Sensitivity; Shape; CMOS; Hall Effect Sensor; Molecular Diagnosis;
Conference_Titel :
Sensors, 2010 IEEE
Conference_Location :
Kona, HI
Print_ISBN :
978-1-4244-8170-5
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2010.5690291
